Science Direct Nutrition Research
Comparative effects of emu and olive oil on aortic early atherosclerosis and associated risk factors in hypercholesterolemic hamsters
Thomas A Wilson, Robert J Nicolosi, Garry Handelman, Subbiah Yoganathan, Timothy Kotyla, Frank Orthoefer, Paul Binford
The comparative cholesterol lowering and anti atherosclerotic properties of emu oil and olive oil were evaluated in four groups (n = 8) of hamsters fed a non-purified diet containing either 10% coconut oil crude and refined, emu oil, and olive oil and 0.05% cholesterol (wt/wt) for 8 weeks. Hamsters fed the olive and emu oil diets had significantly lower concentrations of plasma total cholesterol (- 31 %, and -25%; P < 0.05, respectively) and low-density lipoprotein cholesterol (LDL-C) (-50%, and -41%; P < 0.05, respectively) compared to the coconut oil-fed hamsters, with no significant differences in plasma high- density lipoprotein cholesterol (HDL-C) or triacylglycerol (TAG) concentrations. Compared to the coconut oil fed animals, hamsters fed the emu oil and olive oil-containing diets had reduced aortic cholesterol ester concentrations (-20% and -60%, respectively). The present study suggests that compared to a diet containing coconut oil, both emu oil and olive oil are capable of reducing aortic early
atherosclerosis in hypercholesterolemic hamsters.